A
COMPUTATIONAL
FOUNDATION
FOR LIFE,
BRAINS & MINDS

BARCELONA
COMPUTATIONAL
FOUNDATION

BCOM studies life, brains, and minds as computational phenomena, translating first-principles research into models, methods, and technologies.

 

Our mission is to advance computational neuropsychiatry and neurophenomenology, pioneer neurosynthetic AI, and help build better lives and societies — biological, hybrid, or synthetic.

RESEARCH PILLARS

science with impact

COMPUTATIONAL NEUROPSYCHIATRY

How do we turn whole-brain models and neurophenomenology into precision mental-health care?

ARTIFICIAL & SYNTHETIC INTELLIGENCE

How do we build safer, data-efficient, brain-inspired AI and engineer safer human/AI hybrid ecosystems?

SOCIETY OF AGENTS

How do simulated societies of agents illuminate social learning and cultural evolution?

PHILOSOPHY & ETHICS

DIGITAL PHYSICS & AIT

LIFE & EVOLUTION

EDUCATION & CULTURE

ART & SCIENCE STUDIO

FROM THEORY TO PRACTICE

PATHWAYS TO IMPACT

01

REAL-WORLD APPLICATIONS

BCOM builds models of brains and minds and translates them into applications. A model earns its place by compression: finding the simple structure beneath complex dynamics. The same framework describes a brain, an ecosystem, or a society of agents, and reveals where those dynamics fail into pathology.

Brains · Minds · Societies

02

R&D INFRASTRUCTURE

Every BCOM project runs on shared software, simulation platforms, and architecture. At the centre is the BCOM Ontology: a common language that hands each project the same foundations, so that a brain model and an ecosystem model are built on the same principles and can speak to each other.

Software · Simulation · Ontology

03

IP & SPIN-OUTS

Patents, codebases, and protocols generated by BCOM research, available for licensing or co-development. Selected research lines mature into spin-out companies built with industry partners, so that what starts as a model ends up in the hands of the clinicians, engineers, and institutions who can use it.

Licensing · Co-development

04

TALENT FACTORY

The BCOM Academy brings together people working across the life sciences, art, and humanities, in studios, exchanges, and fellowships. We train scientists who aren't afraid of a deep question, and who keep the pleasure in trying to answer it. Interdisciplinarity and scientific rigour hold the exchange together.

Studios · exchanges · fellowships

THE MOMENT IS RIGHT,
TIME IS NOW

Abundant computational power, rigorous mathematical tools, AI advancement, big data, and exceptional talent have arrived at the same time. BCOM is the shared infrastructure that lets fields speak a common computational language and build a durable foundation for the science of tomorrow.

01. Computational Power

02. Mathematical tools

03. AI advancement

04. Big Data

05. TALENT


Board & leadership

Francesca Castaldo

Co-founder &
Executive Director

Computational neuroscientist focused on brain‑network models and neuropsychiatric disorders.

Giulio Ruffini

Co-founder &
Scientific Director

Physicist and neurotech founder pioneering neuromodulation, computational modeling and clinical translation.

Gustavo Deco

Trustee

ICREA professor at UPF and global leader in whole‑brain modeling and clinical translation.

Ricard Solé

Trustee

ICREA professor and complex‑systems theorist at UPF and Santa Fe Institute; expert in synthetic biology and origins of life.

Karl Friston

Head Scientific Advisory Board

UCL neuroscientist and psychiatrist; architect of SPM, DCM and the Free Energy Principle.

Advisory board

Karl Friston Giulio Ruffini Gustavo Deco Ricard Solé Tomaso Poggio Earl K. Miller Michael Levin Robin Carhart-Harris David Wolpert Xiaosi Gu Joseph Henrich Javier Marquez Ruiz Dirk de Ridder Jordi Garcia-Ojalvo Joana Cabral Edward Rietman Hector Zenil Vladimir Litvak Jorge F. Mejias Miguel Ángel García‑Cabezas  Mehdi Khamassi  Michael D. Fox Giacomo Koch

partnerships